Google Scholar site
Books:
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Zhou, Q. (2025).
Latent Structure and Causality: Inference from Data, World Scientific.
Papers:
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Zhao, Y. and Zhou, Q. (2025).
Causal bandits with backdoor adjustment on unknown Gaussian DAGs. arXiv Preprint, 2502.02020.
[Preprint].
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Chen, A. and Zhou, Q. (2025).
Causal discovery on dependent binary data. Artificial Intelligence and Statistics (AISTATS), accepted.
[Preprint].
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Smith, S. and Zhou, Q. (2024).
Coordinated multi-neighborhood learning on a directed acyclic graph. arXiv Preprint, 2405.15358.
[Preprint].
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Li, H., Madrid Padilla, O.H., and Zhou, Q. (2024).
Learning Gaussian DAGs from network data. Journal of Machine Learning Research, 25 (377): 1-52.
[Reprint].
- Ye, Q., Amini, A.A., and Zhou, Q. (2024).
Federated learning of generalized linear causal networks.
IEEE Transactions on Pattern Analysis and Machine Intelligence, 46: 6623-6636.
[Reprint].
- Kim, D.S. and Zhou, Q. (2023). Structure learning of latent factors via clique search on correlation thresholded graphs. Proceedings of Machine Learning Research, 202 (ICML): 16978-16996. [Reprint].
- Zhou, K., Li, K.C., and Zhou, Q. (2023). Honest confidence sets for high-dimensional regression by projection and shrinkage. Journal of the American Statistical Association, 118: 469-488. [Reprint] [Code and data].
- Huang, J. and Zhou, Q. (2023). Bayesian causal bandits with backdoor adjustment prior. Transactions on Machine Learning Research, 01/2023.
- Amini, A.A., Aragam, B., and Zhou, Q. (2022).
A non-graphical representation of conditional independence via the neighborhood lattice. arXiv Preprint, 2206.05829.
[Preprint].
- Ruiz, R., Madrid Padilla, O.H., and Zhou, Q. (2022). Sequentially learning the topological ordering of directed acyclic graphs with likelihood ratio scores. Transactions on Machine Learning Research, 12/2022.
- Peng, Z., and Zhou, Q. (2022). An empirical Bayes approach to stochastic blockmodels and graphons: shrinkage estimation and model selection. PeerJ Computer Science, 8: e1006. [Reprint].
- Huang, J., and Zhou, Q. (2022). Partitioned hybrid learning of Bayesian network structures. Machine Learning, 111: 1695-1738. [Reprint] [R package].
- Amini, A.A., Aragam, B., and Zhou, Q. (2022). On perfectness in Gaussian graphical models. Proceedings of Machine Learning Research, 151 (AISTATS): 7505-7517.[Reprint].
- Ye, Q., Amini, A.A., and Zhou, Q. (2021). Optimizing regularized Cholesky score for order-based learning of Bayesian networks. IEEE Transactions on Pattern Analysis and Machine Intelligence, 43: 3555-3572.[Reprint].
- Wang, B., and Zhou, Q. (2021).
Causal network learning with non-invertible functional relationships. Computational Statistics and Data Analysis, 156: 107141.
[Preprint].
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Min, S. and Zhou, Q. (2021).
Constructing confidence sets after lasso selection by randomized estimator augmentation. arXiv Preprint, 1904.08018v2.
[Preprint]
[R package].
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Gu, J. and Zhou, Q. (2020).
Learning big Gaussian Bayesian networks: partition, estimation, and fusion. Journal of Machine Learning Research, 21(158): 1-31.
[Reprint].
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Li, J., Zhou, Q., and Yeh, W.W.-G. (2020).
A Bayesian hierarchical model for estimating the statistical parameters in a three-parameter log-normal distribution
for monthly average streamflows.
Journal of Hydrology, 591: 125265.
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Tran, S.S., Zhou, Q.*, and Xiao, X.* (2020).
Statistical inference of differential RNA editing sites from RNA-sequencing data by hierarchical modeling.
Bioinformatics, 36: 2796-2804. (*Corresponding authors.)
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Aragam, B., Amini, A.A., and Zhou, Q. (2019).
Globally optimal score-based learning of directed acyclic graphs in high-dimensions. Advances in Neural Information Processing Systems (NeurIPS), 32: 4450-4462.
[Reprint].
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Aragam, B., Gu, J., and Zhou, Q. (2019).
Learning large-scale Bayesian networks with the sparsebn package.
Journal of Statistical Software, 91: issue 11, 1-38.
[Reprint]
[R package].
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Gu, J., Fu, F., and Zhou, Q. (2019).
Penalized estimation of directed acyclic graphs from discrete data.
Statistics and Computing, 29: 161-176 (DOI: 10.1007/s11222-018-9801-y).
[Preprint]
[R package].
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Amini, A.A., Aragam, B., and Zhou, Q. (2019).
The neighborhood lattice for encoding partial correlations in a Hilbert space. arXiv Preprint, 1711.00991v2.
[Preprint].
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Zhou, Q. and Min, S. (2017).
Estimator augmentation with applications in high-dimensional group inference.
Electronic Journal of Statistics, 11: 3039-3080.
[Reprint].
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Zhou, Q. and Min, S. (2017).
Uncertainty quantification under group sparsity.
Biometrika, 104: 613-632.
[Preprint].
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Kok, J.F., Ridley, D.A., Zhou, Q., Miller, R.L., Zhao, C., Heald, C.L., Ward, D.S., Albani, S., and Haustein, K. (2017).
Smaller desert dust cooling effect estimated from analysis of dust size and abundance.
Nature Geoscience, 10: 274-278.
[Reprint][Commentary]
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Aragam, B., Amini, A.A., and Zhou, Q. (2017).
Learning directed acyclic graphs with penalized neighbourhood regression. arXiv Preprint, 1511.08963v3.
[Preprint].
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Marchetti, Y. and Zhou, Q. (2016).
Iterative subsampling in solution path clustering of noisy big data.
Statistics and Its Interface, 9: 415-431.
[Preprint]
[R package].
(Invited submission for special issue on big data.)
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Aragam, B. and Zhou, Q. (2015).
Concave penalized estimation of sparse Gaussian Bayesian networks.
Journal of Machine Learning Research, 16: 2273-2328.
[Reprint]
[R package].
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Shen, S., Park, J.W., Lu, Z., Lin, L., Henry, M.D., Wu, Y.N., Zhou, Q., and Xing, Y. (2014).
rMATS: Robust and flexible detection
of differential alternative splicing from replicate RNA-Seq data.
Proceedings of the National Academy
of Sciences of USA, 111: E5593-E5601.
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Zhou, Q. (2014).
Monte Carlo simulation for Lasso-type problems by estimator augmentation. Journal of the American Statistical Association, 109: 1495-1516.
[Reprint].
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Marchetti, Y. and Zhou, Q. (2014).
Solution path clustering with adaptive concave penalty. Electronic Journal of Statistics, 8: 1569-1603.
[Reprint]
[R package].
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Cha, M. and Zhou, Q. (2014).
Detecting clustering and ordering binding patterns among transcription factors via point process models. Bioinformatics, 30: 2263-2271.
[Reprint]
[R code].
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Levinson, M. and Zhou, Q. (2014).
A penalized Bayesian approach to predicting sparse protein-DNA binding landscapes. Bioinformatics,
30: 636-643.
[Reprint]
[Software].
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Zhao, K., Lu, Z., Park, J.W., Zhou, Q., and Xing, Y. (2013).
GLiMMPS: Robust statistical model for regulatory variation of alternative splicing using RNA-Seq data.
Genome Biology, 14: R74.
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Lee, Y. and Zhou, Q. (2013).
Co-regulation in embryonic stem cells via context-dependent binding of transcription factors. Bioinformatics,
29: 2162-2168.
[Software].
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Fu, F. and Zhou, Q. (2013).
Learning sparse causal Gaussian networks with experimental intervention:
Regularization and coordinate descent.
Journal of the American Statistical Association, 108: 288-300.
[Code]
[Reprint]
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Tang, W. and Zhou, Q. (2012).
Finding multiple minimum-energy conformations of the hydrophobic-polar protein model
via multidomain sampling.
Physical Review E, 86: 031909.
[Reprint]
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Shen, S., Park, J.W., Huang, J., Dittmar, K.A., Lu, Z., Zhou, Q., Carstens, R.P., and Xing, Y. (2012).
MATS: A Bayesian framework for flexible detection of differential alternative splicing from RNA-Seq data.
Nucleic Acids Research, 40: e61.
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Zhou, Q. (2011).
Multi-domain sampling with applications to structural inference of Bayesian networks.
Journal of the American Statistical Association, 106: 1317-1330.
[Reprint]
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Chen, G. and Zhou, Q. (2011).
Searching ChIP-Seq genomic islands for combinatorial regulatory codes in mouse
embryonic stem cells.
BMC Genomics, 12: 515.
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Zhou, Q. (2011).
Random walk over basins of attraction to construct Ising energy landscapes.
Physical Review Letters, 106: 180602. [Reprint].
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Zhou, Q. (2010).
On weight matrix and
free energy models for sequence motif detection. Journal of Computational
Biology, 17: 1621-1638. [Preprint].
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Mason, M.J., Plath, K., and Zhou, Q. (2010).
Identification of context-dependent motifs by contrasting ChIP
binding data. Bioinformatics, 26: 2826-2832. [Software].
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Chen, G. and Zhou, Q. (2010).
Heterogeneity in DNA multiple alignments: Modeling, inference, and
applications in motif finding. Biometrics, 66: 694-704. [Preprint]
[Software].
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Ouyang, Z., Zhou, Q., and Wong, W.H. (2009).
ChIP-Seq of transcription factors predicts
absolute and differential gene expression in embryonic stem cells. Proceedings of the National Academy
of Sciences of USA,
106: 21521-21526.
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Mason, M.J., Fan, G., Plath, K.,
Zhou, Q.*, and Horvath, S.* (2009).
Signed weighted gene
co-expression network analysis of transcriptional regulation in murine embryonic
stem cells. BMC Genomics, 10: 327. (*Corresponding authors.)
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Gao, K., Zhou, H., Zhang, L., Lee, J.W., Zhou, Q., Hu, S., Wolinsky, L.E.,
Farrell, J., Eibl, G., and Wong, D.T. (2009).
Systemic disease-induced salivary biomarker profiles in mouse models of melanoma
and non-small cell lung cancer. PLoS One, 4: e5875.
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Zhou, Q. and Wong, W.H. (2009).
Energy landscape of a spin-glass model: Exploration and characterization.
Physical Review E, 79: 051117.
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Sridharan, R.*, Tchieu, J.*, Mason, M.J.*, Yachechko, R., Kuoy, E., Horvath, S.,
Zhou, Q., and Plath, K. (2009).
Role of the murine
reprogramming factors in the induction of pluripotency. Cell, 136:
364-377. (*Equally contributed authors.)
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Zhou, Q. and Wong, W.H. (2008).
Reconstructing the energy landscape of a distribution from Monte Carlo samples.
Annals of Applied Statistics, 2: 1307-1331. [Reprint].
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Zhou, Q. and Liu, J.S. (2008).
Extracting sequence features to predict
protein-DNA interactions: A comparative study. Nucleic Acids Research,
36: 4137-4148.
[Preprint] [Supplemental materials].
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Zhou, Q.,
Chipperfield, H., Melton, D.A.,
and Wong, W.H. (2007).
A gene regulatory
network in mouse embryonic stem cells.
Proceedings of the National Academy
of Sciences of USA,
104: 16438-16443.
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Zhou, Q. and Wong, W.H. (2007).
Coupling hidden Markov models for the discovery
of cis-regulatory modules in multiple species. Annals of Applied
Statistics,
1: 36-65. [Reprint]
[Webpage].
- Kou,
S.C.*, Zhou, Q.*, and Wong, W.H. (2006).
Equi-energy sampler with applications in statistical
inference and statistical mechanics (with discussion). Annals of Statistics,
34: 1581-1652. (*Equally contributed authors.) [Reprint] [Discussion
and Rejoinder].
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Johnson, D.S., Zhou, Q.,
Yagi, K., Satoh, N., Wong, W.H., and Sidow, A. (2005).
De novo discovery
of a tissue-specific gene regulatory module in a chordate. Genome
Research,
15: 1315-1324.
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Hong, P., Liu, X.S., Zhou, Q., Lu, X., Liu, J.S., and Wong, W.H. (2005).
A boosting approach for motif modeling
using ChIP-chip data. Bioinformatics, 21: 2636-2643.
- Zhou, Q. and Wong, W.H. (2004).
CisModule: De novo discovery of cis-regulatory
modules by hierarchical mixture modeling. Proceedings of the National Academy of Sciences of USA,
101: 12114-12119. [Webpage].
- Zhou, Q.
and Liu, J.S. (2004).
Modeling within-motif dependence for transcription factor
binding site predictions. Bioinformatics, 20: 909-916. [Webpage]
[Supplementary
Notes].
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Jensen, S.T., Liu, X.S., Zhou, Q., and Liu, J.S. (2004).
Computational discovery of gene regulatory binding motifs:
A Bayesian perspective. Statistical Science, 19: 188-204. [Reprint].
- Zhou, Q. and Li, Y.D. (2003).
Directed variation in evolution strategies. IEEE Transactions on Evolutionary Computation, 7: 356-366.
- Ji, H.K.*, Zhou, Q.*, Wen, F., Xia, H.Y., Lu, X., and Li, Y.D. (2001).
AsMamDB: An alternative splice database of mammals.
Nucleic Acids Research, 29: 260-263. (*Equally contributed authors.)
Other Publications:
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Aragam, B., Gu, J., Amini, A.A., and Zhou, Q. (2017).
Learning high-dimensional DAGs: Provable statistical guarantees and scalable approximation.
NIPS Workshop on Advances in Modeling and Learning Interactions from Complex Data. [Reprint].
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Zhou, Q. (2010). Review of "A Guide
to QTL Mapping with R/qtl" by Broman and Sen. Journal of Statistical
Software, 32: book review 5.
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Zhou, Q. and Gupta, M. (2009).
Regulatory motif discovery: From decoding to
meta-analysis. New Developments in Biostatistics and Bioinformatics,
chp 8, pp. 179-208, World Scientific. [Preprint].
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Liu J.S. and Zhou, Q. (2007).
Predictive modeling approaches for studying protein-DNA binding.
Proceedings of the Fourth International Congress of Chinese Mathematicians, Vol. 4: 151-167,
Higher Education Press and International Press.
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Zhou, Q. (2006).
Detecting cis-regulatory modules by modeling correlated structures in genomic sequences.
Ph.D. Dissertation, Harvard University.